
I could be wrong, but it seems clear that the Enclave is most concerned with a conversation House had before the war with Cooper. In it, House talks about the algorithms and prediction models he used to accurately predict when the bombs would fall. Cooper is skeptical, asking if House is claiming to be a fortune teller. House insists he and Vault-Tec weren’t responsible for starting the apocalypse, despite Moldaver’s suspicions. He states, “I won’t be dropping those bombs, nor anyone at that meeting,” but believes another party was involved – the same one responsible for the creature in the snow. This mysterious entity was possibly seen lurking in the shadows during the meeting, and is long suspected to be connected to the Enclave. While it would be a major change to the story to say the Enclave created deathclaws, it’s plausible they were involved through agents within the military and government. We know from Fallout 2 and 3 that the Enclave extensively experimented with deathclaws after the war.